I suppose I'm writing this update from the fundamental perspective and from the perspective of someone working in healthcare R&D.
When COVID-19 first emerged, various markets got a huge hit. That was expected. The Fed aggressively engaged in QE to prop up the market; DXY trended downwards, and economic growth accelerated. However, there is a price to this, and the Fed will eventually taper their QE programme depending on their estimations of how much the market needs propping up.
I personally don't think the pandemic is over, but it is politically suicidal in many countries to suggest that the pandemic is not, at the very least, starting to wind down. This is why the Fed had a meeting with the CEOs of various big tech companies. This was followed by Microsoft CEO Satya Nadella selling off 50% of his Microsoft shares (remember what he did similarly back in 2018?), and the Fed announcing tapering in Nov.
I personally don't think the bullrun, at least the crypto bullrun, is over yet. Omicron may help matters (maybe), and persuade the Fed to turn dovish again (maybe).
As always, life is uncertain, the financial markets even more so. The logical approach is to avoid determinism, and focus on risk management and positioning over price prediction.