The most significant of them all. Brexit talks end on 15th Oct, as UK PM announced on the start of this week. Meaning of that, GBPUSD started plummeting and now it has reached one of the most crucial dynamic S/R's of the recent history of the pair.
Once the wedge is broken, then I expect aggressive selling which is likely to end at 1.23 level which is considered as major support. Monitor carefully.
Thanks for your time! Good luck! :)