BIIB: Biogen, low risk long term buyReward to risk long term in $BIIB is very attractive here. I've gone long via a calendar spread before the latest FDA approval news, which turned out like a good long position when Biogen's Alzheimer's drug Aduhelm received accelerated approval. Following this, related companies which also have Alzheimer's drugs pending approval (like $LLY) received a dramatic boost. In the case of $LLY, their drug was approved as well a few days later. Both charts are very strong in the long term, showing signs of yearly uptrends present, indicating a multi year rally in these stocks is possible.
Accelerated approval means that the FDA approves the drug due to the possibility that it may provide therapeutic benefit to patients even though there is some uncertainty about the drug’s clinical benefit.
Aduhelm is the first therapy approved for Alzheimer’s disease that is directed at the underlying pathology itself (the presence of amyloid beta plaques in the brain). The clinical trials were the first to show that a reduction in these plaques is expected to lead to a reduction in the clinical decline of this form of dementia.
There is a lot of debate regarding the drug's price tag, as well as the clinical benefit it may or not provide, but I think it's a reasonable bet to make here, from a technical and fundamental standpoint. Valuation wise, the company has very low long term debt to equity, high free cash flow yield and a high earnings yield (trailing twelve months), earnings growth has been negative in the last year, but positive in the previous five years. There is a lot at stake with Aduhelm's potential success, so, don't risk more than you can afford to lose, consider that the yearly uptrend is invalid if price moves below 243.58 to define your position sizing based on your risk appetite.
Cheers,
Ivan Labrie.
Alzheimer
Can SAVA get back to $100 in the short term? $SAVA (Cassava Sciences) saw an insane rally in 2021 from $7 to $145 on the hopes that its groundbreaking Alzheimer's treatment will yield promising results never before seen in the history of the disease. Currently there are no Alzheimer's modifying therapies on the market and if the data surrounding Cassava's main drug, simufilam, is accurate then it could be the first of its kind.
SAVA saw a sell-the-news event when it announced its promising results, suffering a 23% drop on July 29. Soon thereafter a Stat News article was released criticizing Cassava's results, citing a group of independent researchers. The stock dropped a total of 55% from highs.
Is this a buying opportunity? Obviously we are largely delving in uncharted territory and financial analysts/traders won't be able to infer whether the science is reliable or not. However, traders know how market cycles largely work. There is often a second wave of optimism after negative news coverage (whether a short report or a hit piece), driven by those who are willing to speculate.
SAVA is showing a bullish harami on the 1D and it has dropped to the Fibonacci golden pocket level, also at the 100 MA where it has routinely found support. This could be a buying opportunity for those who are in the market for a bit of risk. As long as #SAVA is above the 100 MA, I'm willing to hold it in the mid term and will ride the next wave of positive financial/medical news.
Entry: $79
SL: soft SL with manual monitoring if it breaches the 100 MA
TP: $88, $94, $100
SAVA Stuck At 382It's interesting to see what happens after plotting out fib lines sometimes. SAVA , for instance...using the earlier lows and the recent high as anchors we can see that the 382 fib line has been a very clear area of both support and resistance almost to the exact mark. Sure 236 played this role before the Alzheimer's data but now SAVA has reset back to some familiar territory and, so far, is mimicking its trend before the big breakout, which is 382 fib resistance being an issue. Multiple times in the last few days, this area was tested and SAVA was rejected (including 8/3). BUT with the market seemingly building optimism, it could once again be an important area on the chart to be aware of.
"The biotech industry is well known for volatility. When you’re talking about developing life-changing treatments, there’s a lot to account for. The phase trial process brings the potential for big progress but can also put the brakes on otherwise strong rallies in the market. We recently saw this with companies like Cassava Sciences (NASDAQ: SAVA) and Annovis Bio (NYSE: ANVS ), which were also former penny stocks. Both companies developing Alzheimer’s treatments revealed data that didn’t impress the market at all. In response, shares of both stocks plummeted."
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